Mars Lab

zigzag

A cross-disciplinary research initiative focused on ethical AI implementations in healthcare, ensuring that artificial intelligence enhances patient care while addressing critical ethical challenges.

Healthcare Ethics AI Research Patient Care
When?
2024 - Now
Stage
Research

Collaborators

zigzag

zigzag

Hosting Company

zigzag Project

Overview

Ethical AI in healthcare

The zigzag project explores the complex intersection of artificial intelligence, ethics, and healthcare delivery. Our cross-disciplinary team brings together experts in medicine, AI research, ethics, patient advocacy, and policy to ensure that AI implementations in healthcare settings are effective, fair, transparent, and centered on improving patient outcomes.

Named for the non-linear path that ethical innovation often follows, zigzag acknowledges that progress in healthcare AI requires careful navigation between technical possibilities and ethical imperatives.

Key Challenges We Address

  • Algorithmic bias in clinical decision support systems
  • Privacy and data protection in healthcare AI applications
  • Transparency and explainability of diagnostic AI
  • Equitable access to AI-enhanced healthcare
  • Balancing automation with human medical expertise
  • Regulatory frameworks for healthcare AI applications

Core Principles

  • Patient-centered: Prioritizing patient well-being and autonomy
  • Inclusive: Ensuring AI systems work for diverse populations
  • Transparent: Making AI decision-making processes understandable
  • Evidence-based: Rigorously testing AI systems for safety and efficacy
  • Accessible: Promoting equitable distribution of AI benefits
  • Accountable: Clear responsibility frameworks for AI implementations
"The zigzag project represents a crucial step toward ensuring that AI in healthcare serves humanity's needs while respecting fundamental ethical principles and human dignity." — Dr. Maya Hernandez, Bioethics Director at Health AI Institute

Research

Our investigative focus

Our research methodology combines technical AI development with ethical frameworks, clinical expertise, and patient perspectives to create a holistic approach to healthcare AI.

Research Streams

Fairness in Clinical AI

Investigating methods to detect and mitigate bias in clinical prediction algorithms across diverse patient populations.

Algorithmic Fairness Health Disparities

Explainable Diagnostic AI

Developing techniques that make complex diagnostic AI systems understandable to clinicians and patients.

Explainable AI Clinical Decision Support

Privacy-Preserving Healthcare ML

Creating machine learning frameworks that maintain patient privacy while enabling beneficial uses of health data.

Federated Learning Differential Privacy

Human-AI Collaboration

Studying optimal models for collaboration between healthcare professionals and AI systems.

Human Factors Clinical Workflow

Key Publications

"Ethical Frameworks for Clinical AI Implementation: A Multi-stakeholder Approach"

Journal of Medical Ethics, 2024

Peterson, J., Kim, S., Okonkwo, C., et al.

"Detecting and Mitigating Bias in Cardiovascular Risk Prediction Algorithms"

Nature Machine Intelligence, 2023

Martinez, L., Suzuki, T., O'Neill, B., et al.

"Patient Perspectives on AI in Clinical Care: A Qualitative Analysis"

BMJ Health & Care Informatics, 2023

Wong, A., Patel, R., Mendez, J., et al.

Applications

Ethical AI in action

Our research directly translates into practical applications and frameworks that shape how AI is designed, implemented, and regulated in healthcare settings.

FairDiagnosis

An open-source framework for evaluating and improving fairness in diagnostic AI systems across diverse patient populations.

Deployed in 8 healthcare systems for validation

Technical Documentation

Ethical AI Audit Toolkit

A comprehensive methodology for healthcare organizations to assess AI systems against ethical principles and regulatory requirements.

Adopted by healthcare regulators in 3 countries

Download Resources

PatientUnderstand

Tools for communicating AI-generated healthcare insights to patients in accessible, understandable ways.

Tested with 1,200+ patients across diverse backgrounds

Case Studies

Privacy-First ML Pipeline

A secure infrastructure for healthcare institutions to collaborate on AI development while protecting patient privacy.

Enabling research across 12 institutions without data sharing

Technical Paper

Clinical AI Policy Framework

Guidelines and templates for institutions developing governance policies for clinical AI implementation.

Referenced in national healthcare AI strategies

View Framework

AI Ethics Training

Comprehensive educational program for healthcare professionals on ethical use of AI in clinical settings.

Over 5,000 clinicians trained worldwide

Course Information

Collaborators

Our multidisciplinary team

zigzag brings together a diverse team of experts from across disciplines to ensure a comprehensive approach to ethical AI in healthcare.

Core Partners

University Medical Center

Clinical expertise and real-world healthcare perspectives

Ethics in Technology Institute

Ethical frameworks and governance models

Patient Advocacy Coalition

Patient perspectives and inclusive design

Medical AI Research Lab

Technical expertise in healthcare AI development

Healthcare Policy Institute

Regulatory perspectives and policy recommendations

Global Health Equity Foundation

Focus on health disparities and global access

Join Our Collaboration

We're always looking for new partners who share our commitment to ethical AI implementation in healthcare.